Osteoporosis and rheumatic diseases.

The Role of Monocyte Percentage in Osteoporosis in Male Rheumatic Diseases

Osteoporosis is easily overlooked in male patients, especially in the field of rheumatic diseases mostly prevalent with female patients, and its link to pathogenesis is still lacking. Attenuated monocyte apoptosis from a transcriptome-wide expression study illustrates the role of monocytes in osteoporosis. This study tested the hypothesis that the monocyte percentage among leukocytes could be a...

Exercise in primary prevention of osteoporosis in women.

That oestrogen replacement for osteoporosis prevention should no longer be a bone of contention.

Assessment of activity in SLE: a clinical and serological study.

References BARNETr, E., AND NORDIN, B. E. C. (1960) Clin. Radiol., 11, 166 (The radiological diagnosis of osteoporosis-a new approach) KENNEDY, A. C., SMrrH, D. A., BUCHANAN, W. W., ANDERSON, J. B., SAMUELS, B. B., AND JASANI, M. K. (1974) 'Osteoporosis in rheumatoid arthritis' in 'R' International review of the Ligue Internationale Centre Le Rhumatisme. SMrrH, D. A. (1971) Osteoporosis. Thesis...

How to prevent steroid induced osteoporosis.

The first choice for prevention of corticosteroid osteoporosis is a potent oral bisphosphonate-for example, alendronate or risedronate. Intravenous bisphosphonates should be considered for patients intolerant of the oral route. For patients receiving chronic low dose corticosteroids treatment with calcium and vitamin D may prevent further bone loss. Use of parathyroid hormone is promising.

Osteoblast Role in Rheumatic Diseases

Alterations in osteoblast growth, differentiation and activity play a role in the pathogenesis of several rheumatic diseases, such as rheumatoid arthritis, spondyloarthritides, osteoarthritis, and osteoporosis. In fact, in these rheumatic diseases, abnormal activity of Wnt signaling, receptor activator of nuclear factor-κB (RANK)-RANK ligand (RANKL)-osteoprotegerin (OPG) signaling, bone morphog...